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Among the causes of the condition of anejacujaltion are:


  • Neurological Damage, such as suffered in spinal cord injury (SCI) or as a                                        complication of pelvic surgery

  • Surgical treatment for testicular cancer/retroperitoneal lymph node                                  
    dissection (RPLND)

  • Viral infections and neurological damage

  • Multiple Sclerosis (MS)

  • Spina Bifida

  • Klinefelter's Syndrome

  • Diabetes (Type 1&2)

  • Pre-radical prostatectomy

  • Pre & Post testicular cancer

  • Oncofertility

  • Idiopathaic anejaculation caused by either neurogenic or psychogenic conditions

  • Failure to produce an ejaculate on the day of egg retrieval  for IVF or ICSI


  • A recent application has been the use of EE in male adolescents & teenagers with cancer prior to chemo-radiation therapy


Most cases of ejaculatory failure will be as a result of one of the above listed conditions. More than 90% of SCI men are infertile, most often because of ejaculatory failure and, to a lesser degree, because of impaired spermatogenesis.

An increasing number of Idiopathic Anejaculatory patients have been reported in Asiatic and Middle East countries and similar communities in the U.S. and Europe.


Failure to obtain a semen sample by masturbation is common on the day of Artifical Insemination (AI), in vitro fertilization (IVF), Intracytoplasmic Sperm Injection (ICSI) or other Artifical Reproductive Techniques (ART). Prior to this the subject may have been quite successful in obtaining an ejaculate and even a resulting pregnancy.

Ejaculation may not be possible even with the aid of penile injection, vibration and ejaculatory drugs. When electroejaculation has been used in this instance, the results have been very satisfactory.

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